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This page was last edited on 4 August 2020, at 22:35. (41) Topical Application of Chrysanthemum indicum L. Attenuates the Development of Atopic Dermatitis-Like Skin Lesions by Suppressing Serum IgE Levels, IFN-γ, and IL-4 in Nc/Nga Mice / Sunmin Park, Jung Bok Lee, and Suna Kang / Evidence-Based Complementary and Alternative Medicine, Volume 2012 (2012) / It must be grown outside under sunlight with moist soil. The cancer-specific selectivity suggests the plant extract could be a potential new treatment for human cancer. Levels of 15.63-500 µg C. indicum flower oil/plate did not induce mutagenicity in S. typhimurium and E. coli. CIL treatment dose-dependently reduced severity of clinical symptoms of dorsal skin, ear thickness, and number of mast cells and eosinophils, together with significantly reduced IgE, IgG1, IL-4, and IFN-γ levels and reduced mRNA levels of IFN-γ, IL-4, and IL-13 in dorsal skin lesion. I. Aldose Reductase Inhibitors and Three New Eudesmane-Type Sesquiterpenes, Kikkanols A, B, and C, from the Flowers of Chrysanthemum indicum L. Studies on chemical constituents from flowers of Chrysanthemum indicum. Extracts are preferable hot water extraction or ethanol solvent extraction. 4(5), pp. (2015) 12:1211–1222 / DOI 10.1007/s13762-013-0488-5. Most species originate from East Asia and the center of diversity is in China. Chrysanthemum indicum / Synonyms / The Plant List Anxiolytic-Like Effects of Chrysanthemum indicum Aqueous Extract in Mice: Possible Involvement of GABAA Receptors and 5-HT1A Receptors / Sa-Ik Hong, Seung-Hwan Kwon, Min-Jung Kim, Shi-Xun Ma, Je-Won Kwon, Seung-Min Choi, Soo-Im Choi, Sun-Yeou Kim, Seok-Yong Lee, and Choon-Gon Jang* / Biomol Ther (Seoul) 2012; 20(4): 413-417 • Anti-Inflammatory / Effect on Oxidative Stress: Study evaluated the antioxidant impacts of C. indicum extract on oxidative stress and inflammatory responses in adjuvant-induced arthritis in rats. • Attenuation of Atopic Dermatitis: Study evaluated the effect of topically applied C. indicum in mice with atopic dermatitis (AD)-like symptoms. • Anti-Inflammatory / Effect on Oxidative Stress: • Antioxidant / Prevention of DNA Damage / Flowers: S. Shanthakumar / Water Science & Technology, Volume 77, Issue 6, Anti-Inflammatory Effects of Chrysanthemum indicum Water Extract in RAW 264.7 Cell as a Whole Plant, Antioxidant activities of aqueous extracts from 12 Chinese edible flowers in vitro and in vivo, Chemical (9) • Apoptosis in Human Hepatocellular Carcinoma: CI extract exerted a significant apoptotic effect through a mitochondrial pathway and arrested the cell cycle by regulation of cell-cycle related proteins. Studies on chemical constituents from flowers of Chrysanthemum indicum. (12) / doi: 10.2147/IJN.S53546 CHI extract significantly suppressed LPS-induced NO production and decreased the level of iNOS, IL-iß, COX-2 mRNA expression and downregulated PGE2 expression in a dose-dependent manner. Results suggest a potential alternative for the treatment of AD. 421-426, 4 March, 2010 Plant diversity for mosquito control: A preliminary study / Rathy MC, Sajith U and Harilal CC / International Journal of Mosquito Research 2015; 2 (1): 29-33 Chrysanthemum indicum is a plant of the temperate zone but it can be grown successfully outside the area such as in tropical areas as it is often cultivated in Southeast Asia with moist soil (pH around 6.5) in sunny weather. 3 I. Aldose Reductase Inhibitors and Three New Eudesmane-Type Sesquiterpenes, Kikkanols A, B, and C, from the Flowers of Chrysanthemum indicum L. / YOSHIKAWA M, MORIKAWA T, MURAKAMI T, TOGUCHIDA I, HARIMA S, MATSUDA H / Chem Pharm Bull, VOL.47;NO.3;PAGE.340-345(1999) The ethanol based extract prevented free radical induced DNA damage. (40) A pot mum for all seasons. • Anti-Cancer / Antiproliferative In Human Hepatocellular Cells: Study performed in rats with human cells showed CI extract inhibited proliferation of human hepatocellular cells in a time- and dose-dependent manner without cytotoxicity. (30) ANTIOXIDANT POTENTIAL AND OXIDATIVE DNA DAMAGE PREVENTIVE ACTIVITY OF  CHRYSANTHEMUM INDICUM EXTRACTS / Trishna Debnath, Hai Lan Jin, Md Abul Hasnat, Yunsuk Kim, Nadira Binte Samad, Pyo-Jam Park, Beong Ou Lim / Journal of Food Biochemistry / https://doi.org/10.1111/j.1745-4514.2011.00644.x (35) Chrysanthemum indicum grows up to 0.6 m (24 in) by 0.6 m (24 in). As Moul says, it is suitable for light (sandy), medium (loamy) and heavy (clay) soils. / Chrysanthemum / Plants For A Future Results showed CIE significantly increase cell survival, ALP activity, and calcium deposition, and decreased the production of Reactive Oxygen Species (ROS) and Tumor Necrosis Factor-α (TNF-α) in osteoblasts. indicum - (L.)Des Moul. (22) (33) • Potential for Prostate Cancer / Suppression of STAT3 Activation: Study evaluated the potential effects of C. indicum on signal transducer and activator of transcription 3 (STAT3) signaling pathway in different tumor cells. (4) Dermatologic evaluation of cosmetic formulations containing Chrysanthemum indicum extract / Keun Taek Choi PhD, Jun Ho Kim PhD, Hyung Taek Cho MS, Soon Sung Lim PhD, Sun Soon Kwak PhD, Young Jun Kim PhD / Journal of Cosmetic Dermatology / DOI: 10.1111/jocd.12211 (31) Methanol and water extracts dose dependently inhibited mushroom tyrosinase activity. As Moul says, it is suitable for … (44) Kyoungah Kang / Journal of Korean Biological Nursing Science 2015;17(4):341-347 / http://dx.doi.org/10.7586/jkbns.2015.17.4.341 (25) With higher camphor percentage, the oil of processed flowers greater bacteriostatic activity than air-dried ones. • Enhancement of Osteoblast Function / Prevention of Osteoporosis: Study evaluated the protective effects of Chrysanthemum indicum extract on response of osteoblasts to oxidative stress.

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